The long-term goal of the Division of Cancer Epidemiology and Prevention is to integrate traditional epidemiologic methods with the ever-advancing molecular and omic techniques in cancer research to identify risk factors molecular markers that may serve as tools for cancer prediction, early detection, and prevention. We conduct cancer epidemiology and prevention research in several areas. Learn more below.
Linda Van Horn, PhD, RD is a nutritional epidemiologist. In Dr. Van Horn’s Maternal-Offspring Metabolics: Family Intervention Trial (MOMFIT), an NIH-funded (NIDDK-NHLBI-NICHD) Randomized Clinical Trial (RCT) aiming at controlling gestational weight gain (GWG) and maternal-offspring cardiometabolic outcomes among 300 overweight/obese pregnant women by lifestyle interventions (including physical activity consisting of 30 minutes per day of walking and a healthier, nutrient-dense and low-caloric diet), Dr. Hou and Dr. Van Horn study whether maternal toxic trace elements and essential trace elements are associated with the size and body composition of the offspring at birth and in infancy, which are known to be risk factors for childhood and adulthood obesity, a risk factor itself for various cancers.
Raymond Bergan, MD and Dr. Hou have been developing a collaborative project to study dietary genistein intake, blood genistein levels, and epigenetics in prostate cancer in both Chinese and US men. US men have a very high prostate cancer incidence rate, whereas Chinese men have the lowest incidence and mortality rates in the world. This comparative study will provide information for the first time on the role dietary genistein and its biology and epigenetics play in the US-China prostate cancer incidence and mortality rate disparity.
Lifang Hou, MD, PhD, MS
William Funk, PhD
Wei Zhang, PhD