Chicago Healthy Aging Low-Risk Magnetic Resonance Angiography Study (CHARISMA)

The goal of this study is to better define the mechanisms underlying the protection against clinical CVD events associated with low-risk status in young adulthood, using magnetic resonance angiography of the coronary arteries and cardiac magnetic resonance imaging to examine plaque burden, coronary artery remodeling and cardiac structure/function in older adults (ages 65-84 years) whose risk burden was measured in young adulthood (ages 25-44 years).