Kiang Liu, PhD

Professor and Associate Chair for Research

Dr. Liu received his BS degree in mathematics from Fu-Jen University, Taiwan, in 1970 and his PhD degree in statistics from the University of North Carolina, Chapel Hill, in 1976. That year, he joined Northwestern University Medical School as a postdoctoral fellow in the Department of Community Health and Preventive Medicine's training program in cardiovascular epidemiology sponsored by the National Heart, Lung and Blood Institute (NHLBI). Following his post-doctoral training (1979), he received a research career development award from the NHLBI and became an assistant professor in the department. From 1983 to 1988 he was an associate professor and beginning in 1988 he has been a professor in the Department of Preventive Medicine.

Research Interests

Dr. Liu's research interests are in cardiovascular epidemiology and statistical methodology for epidemiologic research. He has authored or co-authored more than 200 papers or book chapters on these topics. He is the Principal Investigator of the CARDIA Chicago Field Center, an NHLBI - funded longitudinal collaborative study on lifestyle and evolution of cardiovascular risk factors in young adults and Principal Investigator of the MESA Chicago Field Center, an NHLBI - funded longitudinal study on factors related to subclinical cardiovascular disease. He is also the Principal Investigator of the MESA Family Study.

Recent Publications

1. McDermott MM, Liu K, Greenland P, Guralnik JM, Criqui MH, Chan C, Pearce WH, Schneider JR, Ferrucci L, Celic L, Taylor LM, Vonesh E, Martin GJ, Clark E. Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA. 2004; 292:453-461.

2. Daviglus ML, Pirzada A, Liu K, Yan LL, Garside DB, Dyer AR, Hoff JA, Kondos GT, Greenland P, Stamler J. Comparison of Low Risk and Higher Risk Profiles in Middle Age to Frequency and Quantity of Coronary Artery Calcium Years Later. Am J Cardiol. 2004; 94:367-369.

3. Yan LL, Liu K, Matthews KA, Daviglus ML, Ferguson TF, Kiefe CI. Psychosocial factors and risk of hypertension the Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA 2003; 290(16):2138-2148.

4. Daviglus ML, Liu K, Pirzada A, Yan LL, Garside DB, Feinglass J, Guralnik JM, Greenland P, Stamler J. Favorable cardiovascular risk profile in middle age and health-related quality of life in older age. Arch Intern Med. 2003; 163:2460-2468.

5. Carnethon MR, Gidding SS, Nehgme R, Sidney S, Jacobs DR, Liu K. Cardiorespiratory fitness in young adulthood and the development of cardiovascular disease risk factors. JAMA 2003; 290:3092-3100.

6. McDermott MM, Ferrucci L, Guralnik JM, Tian L, Green D, Liu K, Tan J, Liao Y, Pearce WH, Schneider JR, Ridker P, Rifai N, Hoff F, Criqui MH. Elevated levels of inflammation, d-dimer, and homocysteine are associated with adverse calf muscle characteristics and reduced calf strength in peripheral arterial disease. J Am Coll Cardiol. 2007 Aug 28;50(9):897-905.
   
7. McDermott MM, Guralnik JM, Tian L, Ferrucci L, Liu K, Liao Y, Criqui MH. Baseline functional performance predicts the rate of mobility loss in persons with peripheral arterial disease. J Am Coll Cardiol. 2007 Sep 4;50(10):974-82.
8. Vidula H, Tian L, Liu K, Criqui MH, Ferrucci L, Pearce WH, Greenland P, Green D, Tan J, Garside DB, Guralnik J, Ridker PM, Rifai N, McDermott MM. Biomarkers of inflammation and thrombosis as predictors of near-term mortality in patients with peripheral arterial disease: a cohort study. Ann Intern Med. 2008;148:85-93.
9. Detrano R, Guerci AD, Carr JJ, Bild DE, Burke G, Folsom AR, Liu K, Shea S, Szklo M, Bluemke DA, O'Leary DH, Tracy R, Watson K, Wong ND, Kronmal RA. Coronary calcium as a predictor of coronary events in four racial or ethnic groups. N Engl J Med. 2008;358:1336-45
10. Turk A, Kopp P, Colangelo LA, Urbanek M, Wood K, Liu K, Skinner HG, Gapstur SM. Associations of serum sex hormone binding globulin (SHBG) levels with SHBG gene polymorphisms in the CARDIA Male Hormone Study. Am J Epidemiol. 2008 Feb 15;167:412-8.
11. Sternfeld B, Liu K, Quesenberry CP Jr, Wang H, Jiang SF, Daviglus M, Fornage M, Lewis CE, Mahan J, Schreiner PJ, Schwartz SM, Sidney S, Williams OD, Siscovick DS. Changes over 14 years in androgenicity and body mass index in a bi-racial cohort of reproductive age women. J Clin Endocrinol Metab. 2008 Mar 11.
12. Vaidya D, Dobs A, Gapstur SM, Golden SH, Hankinson A, Liu K, Ouyang P. The association of endogenous sex hormones with lipoprotein subfraction profile in the multi-ethnic study of atherosclerosis. Metabolism. 2008 June; 57(6):782-90.

13. Folsom, AR, Kronmal RA, Detrano RC, O'Leary DH, Bild DE, Bluemke DA, Budoff MJ, Liu K, Shea S, Szklo M, Tracy RP, Watson KE, Burke GL. Coronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA). Arch Intern Med. 2008;168:1333-1339.

14. Green D, Foiles N, Chan C, Schreiner PJ, Liu K. Elevated fibrinogen levels and subsequent subclinical atherosclerosis: The CARDIA Study. Atherosclerosis. 2008. [Epub ahead of print.]

15. McDermott MM, Liu K, Ferrucci L, Tian L, Guralnik JM, Green D, Tan J, Liao Y, Pearce WH, Schneider JR, McCue K, Ridker P, Rifai N, Criqui MH. Circulating Blood Markers and Functional Impairment in Peripheral Arterial Disease. J Am Geriatr Soc. 2008 Jul 24. [Epub ahead of print]

16. McDermott MM, Guralnik JM, Ferrucci L, Tian L, Liu K, Liao Y, Green D, Sufit R, Hoff F, Nishida T, Sharma L, Pearce WH, Schneider JR, Criqui MH. Asymptomatic peripheral arterial disease is associated with more adverse lower extremity characteristics than intermittent claudication. Circulation. 2008;117:2484-91.]

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