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Jie (Jenny) Huang, ScD
Dr. Huang received her Bachelor's degree (with honors) in Computer Science
from Wuhan University, Master’s
degree in Biostatistics from University of California,
Los Angeles and Doctoral degree in Biostatistics from Harvard
University. Dr. Huang worked many years as a Biostatistician on a number
of nationwide multicenter AIDS clinical trials at Center
for Biostatistics in AIDS Research, Harvard
School of Public Health. Before joined the faculty in the Department
of Preventive Medicine at Northwestern
University, Dr. Huang was an instructor in medicine at Harvard
Medical School and the director of the methodology/biometry core in the
Section of Clinical Sciences at Brigham
and Women’s Hospital.
Research Interests
Dr. Huang's current research involves a variety of statistical issues arising
in clinical trials and other longitudinal studies, with particular emphasis
on statistical methods and analyses related to HIV infectious disease and cancer.
One area of interest in statistical methods is predicting survival type outcome
measures with information from a large number of predictors. Such question
arises when the scientific interest is to combine clinical information and
gene expression profiling which contains thousands of gene expression measurements
to identify risk groups in terms of survival and predict a patient’s
survival time. The statistical challenge arises because the survival time often
cannot be directly observed and subject to various censoring, and because the
number of independent variables exceeds the number of subjects in the study.
Dr. Huang is also interested in developing model selection procedures in high
dimensional regression with censored data analysis. Another area of research
interest is statistical models and methods with clustered data.
Seclected Recent Publications
Huang J and Harrington DP. Operating Characteristics of Partial Least
Squares in Right-Censored Data Analysis and Its Application in Predicting
the Change of HIV-I RNA. In: Nikulin M. et al. (Eds). Probabilities,
Statistics and Modeling in Public Health. Springer, Cambridge, MA. 2005.
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Huang J and Harrington DP. Iterative Partial Least Squares with Right-Censored
Data Analysis: A Comparison to Other Dimension Reduction Techniques.
Biometrics, 2005; 61(1): 17-24.
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Shea SM, Fieno DS, Schirf BE, Bi X, Huang J, Omary RA, and Li
D. T2-prepared Steady-State Free Procession Blood Oxygen Level-Development
MR Imaging
of Myocardial Perfusion in a Dog Stenosis Model. Radiology, 2005;
236:503-509.
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Finckh A, Simard JF, Duryea J, Liang MH, Huang J, Daneel S,
Forster A, Gabay C, and Guerne PA, for the SCQM program. The
Effectiveness of Anti-TNF
Therapy in Preventing Progressive Radiographic Joint Damage
in Rheumatoid Arthritis. A Population Based Study. Arthritis & Rheumatism, 2005.
In press.
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Omary RA, Gehl JA, Schirf BE, Green JD, Lu B, Pereles FS,
Huang J, Larson AC, Li D. Prospective randomized comparison
of MRI versus x-ray
guided renal angioplasty in swine. Radiology, 2005. In press.
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Green JD, Omary RA, Schirf BE, Tang R, Lu B, Gehl JA, Huang
J, Carr JC, Pereles FS, Li D. Comparison of X-ray Fluoroscopy
and Interventional
MRI for the Assessment of Coronary Artery Stenoses in Swine.
Magnetic Resonance in Medicine, 2005. In press.
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Tripathi A, Kern R, Conley DB, Seiberling K, Klemens JC, Harris
KE, Suh L, Huang J, Grammer LC. Staphylococcal exotoxins and
nasal polyposis:
analysis of systemic and local responses. Am J Rhinol. 2005;
Jul-Aug;19(4):327-33.
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Huang J and Harrington DP. Dimension Reduction in the Linear
Model for Right-Censored Data: Predicting the Change of HIV-1
RNA Levels Using
Clinical and Protease Gene Mutation Data. Lifetime
Data Analysis, 2004; 10(4): 425-443.
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Huang J and Harrington DP. Bootstrap Selection of the Penalty
Parameter in Penalized Partial Likelihood Regression with Right
Censored Data. Biometrics,
2002; 58(4): 781-91.
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Miles SA, Testa M, Huang J, Wade M, Carden J, Scadden DT. Lack of
Antitumor Activity and Intolerance of Interleukin-4
in Patients with Advanced HIV Disease and Kaposi’s sarcoma. J
Interferon Cytokine Res, 2002;
22: 1143-8.
PHONE: 312-503-2424
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