Joan S. Chmiel, PhD

Professor of Preventive Medicine

Dr. Joan S. Chmiel has been on the faculty of Feinberg School of Medicine, Northwestern University, since January 1979 and a member of The Graduate School faculty of Northwestern University since 1988. Her previous academic experience includes 2-1/2 years in the Department of Statistics at the University of Chicago and one year in the Department of Mathematics at the Massachusetts Institute of Technology. Her PhD degree in Statistics was awarded by Stanford University in 1975. Dr. Chmiel was elected a Fellow of the American Statistical Association (ASA) in 1997. Dr. Chmiel currently is an elected Council of Chapters Representative on the ASA Board of Directors for 2004-2006. She is a member of the Acquired Immunodeficiency Syndrome Research Review Committee (AIDSRRC) for the National Institute of Allergy and Infectious Diseases, National Institutes of Health (2004-2008).

Dr. Chmiel is a member of numerous professional statistical organizations and she has held a variety of leadership positions in these organizations. She served on the Regional Advisory Board of the International Biometric Society, Eastern North American Region (ENAR) in 1989-1991, and was ENAR Program Chair for the 1994 Spring ENAR meetings. She served as an elected member of the Regional Committee of ENAR in 1998-2000. Dr. Chmiel was elected Council of Sections Representative for the Biometrics Section of the ASA (1997-1999) and Chair of the ASA Biometrics Section for 2002. Previously she was a member of the Epidemiology and Disease Control Study Section, Subcommittee 2, Division of Research Grants, National Institutes of Health (1991-1995). Dr. Chmiel was statistical reviewer for the Journal of the American Medical Association (JAMA) HIV-AIDS Web Site Editorial Review Panel from its inception through 2000. Since 1997 she has been the Consulting Statistician for the Journal of the American College of Surgeons. She also serves as a statistical reviewer for several other major journals.

Research Interests

Dr. Chmiel’s current research interests are in the epidemiology of HIV-1 infection, statistical methods for epidemiological studies of cancer and AIDS, and clinical trial design and analysis.

Recent Publications

1. Stoser V, Palella FJ Jr, Berzins B, Till M, Leake A, Chmiel JS, Murphy RL. Transient viremia in HIV-infected patients and use of plasma preparation tubes. Clinical Infectious Diseases, 2005 (in press).

2. Chu H, Gange SJ, Yamashita TE, Hoover DR, Chmiel JS, Margolick JB, Jacobson LP. Individual variation in CD4 cell count trajectory among human immunodeficiency virus-infected men and women on long-term highly active antiretroviral therapy: An application using a Bayesian random change-point model. Am J Epidemiology 162:787-797, 2005.

3. Brown TT, Li X, Cole SR, Kingsley LA, Palella FJ, Riddler SA, Chmiel JS, Visscher BR, Margolick JB, Dobs AS. Antiretroviral therapy and markers of insulin resistance in the Multicenter AIDS Cohort Study. AIDS 19:1375-1383, 2005.

4. Schneider MF, Gange SJ, Margolick JB, Detels R, Chmiel JS, Rinaldo C, Armenian HK. Application of case-crossover and case-time-control study designs in analyses of time-varying predictors of T-cell homeostasis failure. Ann Epidemiol 15:137-144, 2005.

5. Rozovsky-Weinberger J, Parada JP, Phan L, Droller DG, Deloria-Knoll M, Chmiel JS, Bennett CL. Delays in suspicion and isolation among hospitalized persons with pulmonary tuberculosis at public and private US hospitals during 1996 to 1999. Chest 127:205-212, 2005.

6. Deloria-Knoll M, Chmiel JS, Moorman AC, Wood KC, Holmberg SD, Palella FJ Jr, and the HIV Outpatient Study (HOPS) Investigators. Factors related to and consequences of adherence to antiretroviral therapy in an ambulatory HIV-infected patient cohort. AIDS Patient Care STDS 18:721-727, 2004.

7. Cole SR, Li R, Anastos K, Detels R, Young M, Chmiel JS, Munoz A. Accounting for leadtime in cohort studies: evaluating when to initiate HIV therapies. Stat Med 23:3351-3363, 2004.

8. Palella FJ Jr, Cole SR, Chmiel JS, Riddler SA, Visscher B, Dobs A, Williams C. Anthropometrics and examiner-reported body habitus abnormalities in the Multicenter AIDS Cohort Study. Clin Infect Dis 38:903-907, 2004.

9. Uphold CR, Deloria-Knoll M, Palella FJ Jr, Parada JP, Chmiel JS, Phan L, Bennett CL. US hospital care for patients with HIV infection and Pneumonia: The role of public, private, and Veterans Affairs hospitals in the early highly active antiretroviral therapy era. Chest 125:548-556, 2004.

10. Sureka A, Parada JP, Deloria-Knoll M, Chmiel JS, Phan L, Lyons TM, Ali S, Yarnold PR, Weinstein RA, DeHovitz JA, Jacobson JM, Goetz MB, Campo RE, Berland D, Bennett CL, Uphold CR. HIV-related pneumonia care in older patients hospitalized in the early HAART era. AIDS Patient Care STDS 18:99-107, 2004.

11. Silverberg MJ, Smith MW, Chmiel JS, Detels R, Margolick JB, Rinaldo CR, O=Brien JS, Munoz A. Fraction of cases of acquired immunodeficiency syndrome prevented by the interactions of identified restriction gene variants. Am J Epidemiol 159:232-241, 2004.

12. Elstein AS, Chapman GB, Chmiel JS, Knight SJ, Chan C, Nadler RB, Kuzel TM, Siston AK, Bennett CL. Agreement between prostate cancer patients and their clinicians about utilities and attribute importance. Health Expect 7:115-125, 2004.

13. Knight SJ, Siston AK, Chmiel JS, Slimack N, Elstein AS, Chapman GB, Nadler RB, Bennett CL. Ethnic variation in localized prostate cancer: a pilot study of preferences, optimism, and quality of life among black and white veterans. Clin Prostate Cancer 3:31-37, 2004.

14. Riddler SA, Li X, Chu H, Kingsley LA, Dobs A, Evans R, Palella F, Visscher B, Chmiel JS, Sharrett A. Longitudinal changes in serum lipids among HIV-infected men on highly active antiretroviral therapy. HIV Med. 2007 Jul;8(5):280-7.
    
15. Schenker N, Monti KL, Cobb GW, Fecso RS, Chmiel JS. Combining features of a frequency table and a stem-and-leaf plot to summarize the American Statistical Association’s strategic activities. Amer Statistician 2007 Aug; Vol. 61, No.3:245-47.
    
16. Lichtenstein KA, Armon C, Buchacz K, Chmiel JS, Moorman AC, Wood KC, Holmberg SD, Brooks JT; the HIV outpatient study (HOPS) investigators. Initiation of Antiretroviral Therapy at CD4 cell counts >/=350 cells/mm3 does not increase incidence or risk of peripheral neuropathy, anemia, or renal insufficiency. J Acquire Immunio Defic Syndr. 2007 Oct 25.
17. Chao C, Jacobson LP, Tashkin D, Martinez-Maza O, Roth MD, Margolick JB, Chmiel JS, Rinaldo C, Zhang ZF, Detels R. Recreational drug use and T lymphocyte subpopulations in HIV - uninfected and HIV - infected men. Drug Alcohol Depend. 2008 Jan 2.
18. Lichtenstein KA, Armon C, Buchacz K, Chmiel JS, Moorman AC, Wood KC, Holmberg SD, Brooks JT; HIV Outpatient Study (HOPS) Investigators. Initiation of antiretroviral therapy at CD4 cell counts >/=350 cells/mm3 does not increase incidence or risk of peripheral neuropathy, anemia, or renal insufficiency. J Acquir Immune Defic Syndr. 2008 Jan;47(1):27-35.

19. D'souza G, Wiley DJ, Li X, Chmiel JS, Margolick JB, Cranston RD, Jacobson LP. Incidence and Epidemiology of Anal Cancer in the Multicenter AIDS Cohort Study. J Acquir Immune Defic Syndr. 2008 Aug 1;48(4):491-499. PMID: 18614927

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