Alfred Rademaker, PhD

Professor

Dr. Rademaker obtained his Ph.D. degree in Statistics from Pennsylvania State University in 1974. He was an Assistant Professor in the Department of Biostatistics, University of North Carolina from 1974 to 1977. He was an Assistant/Associate Professor in the Department of Community Health Sciences, University of Calgary from 1977 to 1987. He has been at Northwestern University in the Department of Preventive Medicine since 1988. In 1999, he became director of the Biostatistics Core Facility of the Robert H. Lurie Comprehensive Cancer Center. He is also the biostatistician for Northwestern University's Cognitive Neurology & Alzheimer's Disease Center.

Research Interests

His general areas of expertise include study design of cancer clinical trials and statistical analysis of data from basic science and clinical cancer studies. Specifically, he is interested in issues related to sample size determination and diagnostic testing. He is also involved in data management, and has strong interests in bioinformatics, as they relate to cancer studies.

Dr. Rademaker is a co-investigator on National Cancer Institute funded studies in the areas of breast cancer and prostate cancer. He has also worked extensively on the statistical analysis of functional swallowing and speech data from head and neck cancer studies.

Recent Publications

1. Logemann JA, Rademaker AW, Pauloski BR, Lazarus CL, Mittal BB, Brockstein B, Maccracken E, Haraf DJ, Vokes EE, Newman LA, Liu D. Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation. Head Neck. 2006 Jan;28(1):64-73.

2. Wicklund AH Johnson N Rademaker A Weitner BB Weintraub S. Word list versus story memory in Alzheimer disease and frontotemporal dementia. Alzheimer Dis Assoc Disord. 2006;20(2):86-92.

3. Querfeld C, Rizvi MA, Kuzel TM, Guitart J, Rademaker A, Sabharwal SS, Krett NL, Rosen ST. The Selective Protein Kinase C beta Inhibitor Enzastaurin Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines through the AKT Pathway. J Invest Dermatol 2006;126:1641-1647.

4. Hoekstra A, Singh DK, Garb M, Arekapudi S, Rademaker A, Lurain JR. Participation of the general gynecologist in surgical staging of endometrial cancer: Analysis of cost and perioperative outcomes. Gynecol Oncol. 2006;103:897-901.

5. Bhandare D, Nayar R, Bryk M, Hou N, Cohn R, Golewale N, Parker NP, Chatterton RT, Rademaker A, Khan SA. Endocrine biomarkers in ductal lavage samples from women at high risk for breast cancer. Cancer Epidemiol Biomarkers Prev. 2005;14:2620-2627.

6. Kimmel Z, Ratner D, Kim KY, Wayne JD, Rademaker AW, Alam M. Peripheral excision Margins for Dermatofibrosarcoma Protuberans: A Meta-analysis of Special Data. Am Surg Oncol. 2007 Jul;14(7):2113-20. Epub 2007 Apr 15.

7. Lazarus CL. Logemann JA, Pauloski BR, Rademaker AW, Helenowski IB, Vonesh EF, Maccracken E. Mittal BB, Vokes EE, Haraf DJ. Effects of radiotherapy with or without chemotherapy on tongue strength and swallowing in patients with oral cancer. Head Neck. 2007 Jul;29(7):632-7.

8. Fitzgibbon ML, Ferreira MR, Dolan NC, Davis TC, Rademaker AW, Wolf MS, Dachao Liu, Gorby N, Schmitt BP, Bennett CL. Process evaluation in an intervention designed to improve rates of colorectal cancer screening in a VA Medical Center. Health Promot Pract.2007 Jul;8(3):273-81.

9. Fox-Canale AM, Hope TJ, Martinson J, Lurain JR, Rademaker AW, Bremer JW, Landay A, Spear GT, Lurain NS. Human cytomegalovirus and human immunodeficiency virus type-1 co-infection in human cervical tissue. Virology. 2007 Aug 21.

10. Logemann JA, Pauloski BR, Rademaker AW, Lazarus CL, Gaziano J, Stachowiak L, Newman L, Maccracken E, Santa D, Mittal B. Swallowing disorders in the first year after radiation and chemoradiation. Head Neck. 2007 Sep 4.
11. Logemann JA, Pauloski BR, Rademaker AW, Lazarus CL, Gaziano J, Stachowiak L, Newman L, MacCracken E, Santa D, Mittal B. Swallowing disorders in the first year after radiation and chemoradiation. Head Neck. 2008 Feb;30(2):149-58.
12. Rosenson RS, Huskin AL, Wolff DA, Helenowski IB, Rademaker AW. Fenofibrate reduces fasting and postprandial inflammatory responses among hypertriglyceridemia patients with the metabolic syndrome. Atherosclerosis. 2008 Jan 31; [Epub ahead of print]
13. Mesulam M, Wicklund A, Johnson N, Rogalski E, Lèger GC, Rademaker AW, Weintraub S, Bigio EH. Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia. Ann Neurol. 2008 Apr 15 [Epub ahead of print]


14. Do TV, Kubba LA, Antenos M, Rademaker AW, Sturgis CD, Woodruff TK. The role of activin A and Akt/GSK signaling in ovarian tumor biology. Endocrinology. 2008 May 1.
15. Rosenson RS, Husking AL, Wolff DA, Helenowski IB, Rademaker AW. Fenofibrate reduces fasting and postprandial inflammatory responses among hypertriglyceridemia patients with the metabolic syndrome. Atherosclerosis. 2008 Jun; 198(2):381-8.
16. Do TV, Kubba LA, Antenos M, Rademaker AW, Sturgis CD, Woodruff TK. The role of activin A and Akt/GSK signaling in Ovarian tumor biology. Endocrinology. 2008 May 1. [Epub ahead of print]
17. Rosenson RS, Huskin AL, Wolff DA, Helenowski IB, Rademaker AW. Fenofibrate reduces fasting and postprandial inflammatory responses among hypertriglyceridemia patients with the metabolic syndrome. Atherosclerosis. 2008 Jun;198(2):381-8.

PHONE: 312-908-1970
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